Print this page

Liver Center - Wilson Disease



Definition Incidence Risk Factors/Cause
The inability of copper to be excreted in bile causing its accumulation in the liver, brain, kidneys and cornea. Adolescents and young adults

Rare
Autosomal inherited disease
Symptoms Diagnosis Treatment/Prevention
Accumulation of copper in liver tissue

Hemolytic anemia

Low ceruloplasmin

Neurologic impairments

Kayser-Fleischer rings
Medical history

Physical exam

Blood tests

Liver biopsy
Penicillamine, trientine or zinc therapy

Prednisone therapy

Liver transplantation in severe, chronic cases