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Liver Center - Acute Liver Failure



Definition Incidence Risk Factors/Cause
Inability of the liver to function due to chemical/drug toxicity, acute flare of hepatitis or liver trauma Uncommon Acetaminophen toxicity

Viral hepatitis

Drug reaction

Ischemic hepatitis

Wilson disease

Autoimmune hepatitis

Fatty liver of pregnancy

Reye’s syndrome

Mushroom poisoning
Symptoms Diagnosis Treatment/Prevention
Jaundice

Hepatocellular necrosis

Encephalopathy
Medical history

Physical exam

Blood tests

Liver biopsy
Intensive monitoring

Emergent evaluation for orthotopic liver transplant